Publications
The Advanced Solutions team and collaborators routinely publish the groundbreaking research. When you choose an Advanced Solutions product, you get a partner in research there to support you throughout your discovery.
Search Publications
Point-of-use, automated fabrication of a 3D human liver model supplemented with human adipose microvessels
Sarah M. Moss, Jillian Schilp, Maya Yaakov, Madison Cook, Erik Schuschke, Brandon Hanke, Hannah A. Strobel, James B. Hoying
Jun 27, 2022
SLAS Discovery
A Biofabrication Strategy for a Custom-Shaped, Non-Synthetic Bone Graft Precursor with a Prevascularized Tissue Shell
Sarah M. Moss, Monica Ortiz-Hernandez, Dmitry Levin, Chris A. Richburg, Thomas Gerton, Madison Cook, Jeffrey J. Houlton, Zain H. Rizvi, Paul C. Goodwin, Michael Golway, Beth Ripley, James B. Hoying
Mar 9, 2022
Frontiers in Bioengineering and Biotechnology
The Evaluation of Neovessel Angiogenesis Behavior at Tissue Interfaces
Hannah A. Strobel, James B. Hoying
Jan 31, 2022
Methods in Molecular Biology: Angiogenesis
A Preliminary Study for an Intraoperative 3D Bioprinting Treatment of Severe Burn Injuries
Marion Albouy, Adeline Desanlis, Sophie Brosset, Celine Auxenfans, Edwin-Joffrey Courtrial, Kyle Eli, Scott Cambron, Justin Palmer, Luciano Vidal, Amelie Thepot, Morgan Dos Santos, Christophe A. Marquette
Jan 1, 2022
Plastic and Reconstructive Surgery - Global Open
Cell-based therapies for vascular regeneration: Past, present and future
Yasaman Aghazadeh, Safwat T. Khan, Blessing Nkennor, Sara S. Nunes
Sep 1, 2021
Pharmacology & Therapeutics
Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
Yasaman Aghazadeh, Frankie Poon, Farida Sarangi, Frances T.M. Wong, Safwat T. Khan, Xuetao Sun, Rupal Hatkar, Brian J. Cox, Sara S. Nunes, M. Cristina Nostro
Aug 31, 2021
Cell Stem Cell
Quantifying vascular density in tissue engineered constructs using machine learning
Hannah A. Strobel, Alex Schultz, Sarah M. Moss, Rob Eli, James B. Hoying
Apr 27, 2021
Frontiers in Physiology - Computational Physiology and Medicine
Vascularized adipocyte organoid model using isolated human microvessel fragments
Hannah A. Strobel, Thomas Gerton, James B. Hoying
Apr 7, 2021
Biofabrication, Volume 13, Number 3
3D Bioprinted Bacteriostatic Hyperelastic Bone Scaffold for Damage-Specific Bone Regneration
Mohammadreza Shokouhimehr, Andrea S. Theus, Archana Kamalakar, Liqun Ning, Cong Cao, Martin L. Tomov, Jarred M. Kaiser, Steven Goudy, Nick J. Willett, Ho Won Jang, Christopher N. LaRock, Philip Hanna, Aron Lechtig, Mohamed Yousef, Janaiana Da Silva Martins, Ara Nazarian, Mitchel B. Harris, Morteza Mahmoudi, Vahid Serpooshan
Mar 30, 2021
Polymers, Volume 13, Edition 7
Maturation of in situ bioprinting
James B. Hoying
Jan 26, 2021
Journal of 3D Printing in Medicine, Volume 4, Number 4
Improvement of islet transplantation by the fusion of islet cells with functional blood vessels
Lisa Nalbach, Leticia P. Roma, Beate M. Schmitt, Vivien Becker, Christina Korbel, Selina Wrublewsky, Mandy Pack, Thomas Spater, Wolfgang Metzger, Maximilian M. Menger, Florian S. Frueh, Claudia, Gotz, Haopeng, Lin, Joseline E. Manning Fox, Patrick E. MacDonald, Michael D. Menger, Matthias W. Laschke, Emmanuel, Ampofo
Jan 11, 2021
EMBO Molecular Medicine, Volume 13
An Integrated Design of Polypseudorotaxane-Based Sea Cucumber Mimic
Longyu Li, Qianming Lin, Miao Tang, Esther H.R. Tsai, Chenfeng Ke
Jan 1, 2021
Angwandte Chemie
Microvascular Fragments: More Than Just Natural Vascularization Units
Matthias W. Laschke, Thomas Spater, Michael D. Menger
Jan 1, 2021
Trends in Biotechnology, Volume 39, Issue 1
3D Bioprinting of Neural Tissues
Melissa Cadena, Liquin Ning, Alexia King, Boeun Hwang, Linqi Jin, Vahid Serpooshan, Steven A. Sloan
Nov 16, 2020
Advanced Healthcare Materials, Volume 10, Issue 15
Mechanical Considerations of Bioprinted Tissues
Hannah A. Strobel, Sarah M. Moss, James B. Hoying
Oct 28, 2020
Frontiers in Mechanical Engineering - Digital Manufacturing
Transplanted microvessels improve pluripotent stem cell-derived cardiomyocyte engraftment and cardiac function after infarction in rats
Xuetao Sun, Jun Wu, Beiping Qiang, Rocco Romagnuolo, Mark Gagliardi, Gordon Keller, Michael A. Laflamme, Ren-Ke Li, Sara S. Nunes
Sep 23, 2020
Science Translational Medicine, Volume 12, Issue 562
Scaffold Architecture and Matrix Strain Modulate Mesenchymal Cell and Microvascular Growth and Development in a Time Dependent Manner
Gennifer Chiou, Elysa Jui, Allison C. Rhea, Aparna Gorthi, Solaleh Miar, Francisca M. Acosta, Cynthia Perez, Yasir Suhail, Kshitiz, Yidong Chen, Joo L. Ong, Rena Bizios, Christopher Rathbone, Teja Guda
Aug 18, 2020
Cellular and Molecular Bioengineering, Volume 13
A Straightforward Approach to Engineer Vascularized Adipose Tissue Using Microvascular Fragments
Francisca M. Acosta, Katerina Stojkova, Erc M. Brey, Christopher R. Rathbone
Aug 17, 2020
Tissue Engineering Part A, Volume 26, Numbers 15-16
Stromal Cells Promote Neovascular Invasion Across Tissue Interfaces
Hannah A. Strobel, Steven A. LaBelle, Laxminarayanan Krishnan, Jacob Dale, Adam Rauff, A. Marsh Poulson IV, Nathan Bader, Jason E. Beare, Klevis Aliaj, Jeffrey A. Weiss, James B. Hoying
Aug 14, 2020
Frontiers in Physiology - Vascular Physiology
A comparative study in the printability of a bioink and 3D models across two bioprinting platforms
Matthew Alonzo, Erick Dominguez, Fabian Alvarez-Primo, Amado Quinonez, Erik Munoz, Jazmin Puebla, Antonio Barron, Luis Aguirre, Ana Vargas, Jean M. Ramirez, Binata Joddar
Apr 1, 2020
Materials Letters, Volume 264
3D Printing of Gelled and Cross-Linked Cellulose Solutions; an Exploration of Printing Parameters and Gel Behaviour
Tim Huber, Hossein Najaf Zadeh, Sean Feast, Thea Roughan, Conan Fee
Mar 27, 2020
Bioengineering, Volume 7, Edition 2
Intraoperative Bioprinting: Repairing Tissues and Organs in a Surgival Setting
Yang Wu, Dino J. Ravnic, Ibrahim T. Ozbolat
Feb 24, 2020
Trends in Biotechnology
Biofabrication of tissue perfusion systems and vasculatures
Hannah A. Strobel, Sarah M. Moss, James B. Hoying
Jan 1, 2020
Rapid Prototyping of Biomaterials - Techniques in Additive Manufacturing, Second Edition
Triggered micropore-forming bioprinting of porous viscoelastic hydrogels
Guangyu Bao, Tao Jiang, Hossein Ravanbakhsh, Alicia Reyes, Zhenwei Ma, Mitchell Strong, Huijie Wang, Joseph M. Kinsella, Jainyu Li, Luc Mongeau
Jan 1, 2020
Material Horizons, Issue 9
Insulin-like growth factor 1 stimulates the angiogenic activity of adipose tissue-derived microvascular fragments
Matthias W. Laschke, Elena Kontaxi, Claudia Scheuer, Alexander Heb, Philipp Karschnia, Michael D. Menger
Sep 27, 2019
Journal of Tissue Engineering and Regenerative Medicine, Volume 10
Characterizing the Process Physics of Ultrasound-Assisted Bioprinting
Parth Chansoria, Rohan Shirwaiker
Sep 25, 2019
Scientific Reports, Volume 9
Imaging the Dynamic Interaction Between Sprouting Microvessels and the Extracellular Matrix
Adam Rauff, Steven A. LaBelle, Hannah A. Strobel, James B. Hoying, Jeffrey A. Weiss
Aug 22, 2019
Frontiers in Physiology - Biophysics
Type I Diabetes Delays Perfusion and Engraftment of 3D Constructs by Impinging on Angiogenesis; Which can be Rescued by Hepatocyte Growth Factor Supplementation
Wafa Altalhi, Rupal Hatkar, James B. Hoying, Yasaman Aghazadeh, Sara S. Nunes
May 21, 2019
Cellular and Molecular Bioengineering, Volume 12
Large 3D bioprinted tissue: Heterogeneous perfusion and vascularization
Lea Pourchet, Emma Petiot, Celine Loubiere, Eric Olmos, Morgan Dos Santos, Amelie Thepot, Blum J. Loic, Chistophe A. Marquette
Mar 1, 2019
Bioprinting, Volume 13, Edition 39
Individual cell-only bioink and photocurable supporting medium for 3D printing and generation of engineered tissues with complex geometries
Oju Jeon, Yu Bin Lee, Hyoen Jeong, Sang Jin Lee, Derrick Wells, Eben Alsberg
Jan 1, 2019
Material Horizons, Issue 8
Subnormothermic short-term cultivation improves the vascularization capacity of adipose tissue-derived microvascular fragments
Matthias W. Laschke, Alexander Heb, Claudia Scheuer, Philipp Karschnia, Michael D. Menger
Nov 23, 2018
Journal of Tissue Engineering and Regenerative Medicine, Volume 13, Issue 2
Prevascularization of collagen-glycosaminoglycan scaffolds: stromal vascular fraction versus adipose tissue-derived microvascular fragments
Thomas Spater, Florian S. Frueh, Ruth M. Nickels, Michael D. Menger, Matthias W. Laschke
Nov 13, 2018
Journal of Biological Engineering
Effects of locally applied adipose tissue-derived microvascular fragments by thermoresponsive hydrogel on bone healing
M. Orth, M.A.B. Altmeyer, C. Scheuer, B.J. Braun, J.H. Holstein, D. Eglin, M. D'Este, T. Histing, M.W. Laschke, T. Pohlemann, M.D. Menger
Sep 1, 2018
Acta Biomaterialia, Volume 77
Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting
Florian S. Frueh, Thomas Spater, Christina Korbel, Claudia Scheuer, Anna C. Simson, Nicole Lindenblatt, Pietro Giovanoli, Michael D. Menger, Matthias W. Laschke
Jul 20, 2018
Scientific Reports, Volume 8
Erythorpoietin promotes network formation of transplanted adipose tissue-derived microvascular fragments
P Karschnia, C Scheuer, A Heb, T Spater, M.D. Menger, M.W. Laschke
May 9, 2018
Eur Cell Mater, Volume 35
Effects of cryopreservation on adipose tissue-derived microvascular fragments
Matthias W. Laschke, Philipp Karschnia, Claudia Scheuer, Alexander Heb, Wolfgang Metzger, Michael D. Menger
Apr 1, 2018
Journal of Tissue Engineering and Regnerative Medicine, Volume 12, Issue 4
Enoxaparin does not affect network formation of adipose tissue-derived microvascular fragments
Thomas Spater, Florian S. Frueh, Philipp Karschnia, Michael D. Menger, Matthias W. Laschke
Jan 1, 2018
Wound Repair and Regeneration, Volume 26, Issue 1
Potentials and limitations of Integra® flowable wound matrix seeded with adipose tissue-derived microvascular fragments
T Spater, F.S. Frueh, M.D. Menger, M.W. Laschke
Apr 5, 2017
European Cells and Materials, Volume 33
Bioengineering cardiac constructs using 3D printing
Vahid Serpooshan, Morteza Mahmoudi, Daniel A. Hu, James B. Hu, Sean M. Wu
Mar 3, 2017
Journal of 3D Printing in Medicine, Volume 1, Number 2
Diabetes impairs arterio-venous specification in engineered vascular tissues in a perivascular cell recruitment-dependent manner
Wafa Altalhi, Xuetao Sun, Jeremy M. Sivak, Mansoor Husain, Sara S. Nunes
Mar 1, 2017
Biomaterials, Volume 119
Adipose Tissue-Derived Microvascular Fragments Improve Vascularization, Lymphangiogenesis, and Integration of Dermal Skin Substitutes
Florian S. Frueh, Thomas Spater, Nicole Lindenblatt, Maurizio Calcagni, Pietro Giovanoli, Claudia Scheuer, Michael D. Menger, Matthias W. Laschke
Jan 1, 2017
Journal of Investigative Dermatology, Volume 137, Issue 1
Seeding Density is a Crucial Determinant for the In Vivo Vascularisation Capacity of Adipose Tissue-Derived Microvascular Fragments
T. Spater, C. Korbel, F.S. Frueh, R.M. Nickels, M.D. Menger, M.W. Laschke
Jan 1, 2017
European Cells and Materials, Volume 34
Microvascular Fragment Transplantation Improves Rat Dorsal Skin Flap Survival
Randolph Stone II, Christopher R. Rathbone
Dec 23, 2016
Plastic and Reconstructive Surgery - Global Open, Volume 4, Issue 12
Effects of macrophage-activating lipopeptide-2 (MALP-2) on the vascularisation of implanted polyurethane scaffolds seeded with microvascular fragments
C. Grasser, C. Scheuer, J. Parakenings, T. Tschernig, D. Eglin, M.D. Menger, M.W. Laschke
Jul 8, 2016
European Cells and Materials, Volume 32
Vascularization strategies of engineered tissues and their application in cardiac regeneration
Xuetao Sun, Wafa Altalhi, Sara S. Nunes
Jan 15, 2016
Advanced Drug Delivery Reviews, Volume 96
Adipose tissue-derived microvascular fragments: natural vascularization units for regenerative medicine
Matthias W. Laschke, Michael D. Menger
Aug 1, 2015
Trends in Biotechnology, Volume 33, Issue 8
In Silico Investigation of Angiogenesis with Growth and Stress Generation Coupled to Local Extracellular Matrix Density
Lowell T. Edgar, James B. Hoying, Jeffrey A. Weiss
May 21, 2015
Annals of Biomedical Engineering, Volume 43
Large Scale Time Series Microscopy of Neovessel Growth During Angiogenesis
Urs Utzinger, Brenda Baggett, Jeffrey A. Weiss, James B. Hoying, Lowell T. Edgar
Mar 21, 2015
Angiogenesis, Volume 18, Issue 3
A Couple Model of Neovessel Growth and Matrix Mechanics Describes and Predicts Angiogenesis In Vitro
Lowell T. Edgar, Steve A. Maas, James E. Guilkey, Jeffrey A. Weiss
Nov 28, 2014
Biomechanics and Modeling in Mechanobiology, Volume 14
Characterization and multilineage potential of cells derived from isolated microvascular fragments
Jennifer S. McDaniel, Marcello Pilia, Catherine L. Ward, Beth E. Pollot, Christopher R. Rathbone
Nov 1, 2014
Journal of Surgical Research - Vascular, Volume 192, Issue 1
Transplantation and perfusion of microvascular fragments in a rodent model of volumetric muscle loss injury
M. Pilia, J.S. McDaniel, T. Guda, X.K. Chen, R.P. Rhoads, R.E. Allen, B.T. Corona, C.R. Rathbone
Jul 14, 2014
European Cells and Materials, Volume 28
Pericytes from Microvessel Fragment Produce Type IV Collagen and Multiple Laminin Isoforms
Hoon Jeon, Masaaki Ono, Chino Kumagai, Kiyoshi Miki, Akihito Morita, Yasuo Kitagawa
Jun 12, 2014
Bioscience, Biotechnology, and Biochemistry, Volume 60, Issue 5
Cell-generated traction forces and the resulting matrix deformation modulate microvascular alignment and growth during angiogenesis
Clayton J. Underwood, Lowell T. Edgar, James B. Hoying, Jeffrey A. Weiss
May 9, 2014
American Journal of Physiology - Heart and Circulatory Physiology
Mechanical Interaction of Angiogenic Microvessels with the Extracellular Matrix
Lowell T. Edgar, James B. Hoying, Urs Utzinger, Clayton J. Underwood, Laxminarayanan Krishnan, Brenda K. Baggett, Steve A. Maas, James E. Guilkey, Jeffrey A. Weiss
Feb 5, 2014
Journal of Biomechanical Engineering, Volume 136, Issue 2
Extracellular Matrix Density Regulates the Rate of Neovessel Growth and Branching in Sprouting Angiogenesis
Lowell T. Edgar, Clayton J. Underwood, James E. Guilkey, James B. Hoying, Jeffrey A. Weiss
Jan 22, 2014
PLoS One
Hypoxia Simultaneously Alters Satellite Cell-Mediate Angiogensis and Hepatocyte Growth Factor Expression
K.L. Flann, C.R. Rathbone, L.C. Cole, X. Liu, R.E. Allen, R.P. Rhoads
Oct 5, 2013
Journal of Cellular Phyisology, Volume 229, Issue 5
Vascularisation of porous scaffolds is improved by incorporation of adipose tissue-derived microvascular fragments
M.W. Laschke, S. Kleer, C. Scheuer, S. Schuler, P. Garcia, D. Eglin, M. Alini, M.D. Venger
Dec 1, 2012
European Cells and Materials, Volume 24
A Computational Model of In Vitro Angiogenesis based on Extracellular Matrix Fiber Orientation
Lowell T. Edgar, Scott C. Sibole, Clayton J. Underwood, James E. Guilkey, Jeffrey A. Weiss
Apr 19, 2012
Computer Methods in Biomechanics and Biomedical Engineering, Volume 16, Issue 7
Engineering fibrin polymers through engagement of alternative polymerization mechanisms
Sarah E. Stabenfeldt, Merek Gourley, Laxminarayanan Krishnan, James B. Hoying, Thomas H. Barker
Jan 1, 2012
Biomaterials, Volume 33, Issue 2
Vessel Arterial-Venous Plasticity in Adult Neovascularization
Sara S. Nunes, Harish Rekapally, Carlos C. Chang, James B. Hoying
Nov 21, 2011
PLoS One
Determinants of Microvascular Network Topolgies in Implanted Neovasculatures
Carlos C. Chang, Laximarayanan Krishnan, Sara S. Nunes, Kenneth H. Church, Lowell T. Edgar, Eugene D. Boland, Jeffrey A. Weiss, Stuart K. Williams, James B. Hoying
Nov 3, 2011
Arteriosclerosis, Thrombosis, and Vascular Biology, Volume 32
Implanted Microvessels Progress through Distinct Neovascularization Phenotypes
Sara S. Nunes, Kevin A. Greer, Chad M. Stiening, Helen YS. Chen, Kameha R. Kidd, Mark A. Schwartz, Chris J. Sullivan, Harish Rekapally, James B. Hoying
Jan 1, 2011
Microvascular Research, Volume 79, Issue 1
Angiogenic potential of microvessel fragments is independent of the tissue of origin and can be influenced by the cellular composition of the implants
Sara S. Nunes, Laxminarayanan Krishnan, Carter S. Gerard, Jacob R. Dale, Melissa A. Maddie, Richard L. Benton, James B. Hoying
Oct 17, 2010
Microcirculation, Volume 17, Issue 7
Encapsulation of ePTFE in prevascularized collagen leads to peri-implant vascularization with reduced inflammation
Gabriel Gruionu, Alice L. Stone, Mark A. Schwartz, James B. Hoying, Stuart K. Williams
Aug 23, 2010
Journal of Biomedical Materials Research Part A, Volume 95A, Issue 3
Microvascular Transplantation After Acute Myocardial Infarction
Benjamin R. Shepherd, James B. Hoying, Stuart K. Williams
Jan 17, 2010
Advances in Tissue Engineering, Volume 1 - Angiogenesis
Angiogenesis in a Microvascular Construct for Transplantation Depends on the Method of Chamber Circulation
Carlos C. Chang, Sara S. Nunes, Scott C. Sibole, Laxminarayanan Krishnan, Stuart K. Williams, Jeffrey A. Weiss, James B. Hoying
Dec 18, 2009
Tissue Engineering Part A, Volume 16, Number 3
Satellite cell-mediated angiogenesis in vitro coincides with a functional hypoxia-inducible factor pathway
R.P. Roads, R. M. Johnson, C.R. Rathbone, X. Liu, C. Temm-Grove, S.M. Sheehan, James B. Hoying, R.E. Allen
Jun 1, 2009
American Journal of Physiology - Cell Physiology
An Islet-Stabilizing Implant Constructed Using a Preformed Vasculature
Alton M. Hiscox, Alice L. Stone, Sean Limesand, James B. Hoying, Stuart K. Williams
Mar 11, 2008
Tissue Engineering Part A, Volume 14, Number 3
Effect of Mechanical Boundary Conditions on Orientation of Angiogenic Microvessels
Laxminarayanan Krishnan, Clayton J. Underwood, Steve Maas, Benjamin J. Ellis, Tejas C. Kode, James B. Hoying, Jeffrey A. Weiss
Feb 28, 2008
Cardiovascular Research, Volume 78, Issue 2
Interaction of Angiogenic Microvessels with the Extracellular Matrix
Laxminarayanan Krishnan, James B. Hoying, Hoa Nguyen, Helen Song, Jeffrey A. Weiss
Oct 12, 2007
American Journal of Physiology - Heart and Circulatory Physiology
Live imaging of collagen remodeling during angiogenesis
Nathaniel D. Kirkpatrick, Stylianos Andreou, James B. Hoying, Urs Utzinger
Jun 1, 2007
American Journal of Physiology - Heart and Circulatory Physiology
Directed Three-Dimensional Gowth of Microvascular Cells and Isolated Microvessel Fragments
Carlos C. Chang, James B. Hoying
Mar 1, 2006
Cell Transplantation, Volume 15
The non-proteolytically active thrombin peptide TP508 stimulates angiogenic sprouting
Keri B. Vartanian, Helen Y.S. Chen, Janelle Kennedy, Shaleen K. Beck, James T. Ryaby, Hali Wang, James B. Hoying
Jul 14, 2005
Journal of Cellular Phyisology, Volume 206, Issue 1
Rapid Perfusion and Network Remodeling in a Microvascular Construct After Implantation
Benjamin R. Shepherd, Helen Y.S. Chen, Cynthia M. Smith, Gabriel Gruionu, Stuart K. Williams, James B. Hoying
Feb 26, 2004
Arteriosclerosis, Thrombosis, and Vascular Biology, Volume 24
Parathyroid-induced angiogenesis is VEGF-dependent
W. Bradford Carter, Kenny Uy, Michael D. Ward, James B. Hoying
Sep 1, 2000
Surgery, Volume 128, Issue 3
Successful Autotransplantation of Microvessel Fragments into the Rat Heart
M. Nakano, Y. Nakajima, S. Kudo, Y. Tsuchida, H. Nakamura, O. Fukuda
Jan 1, 1999
Eurpoean Surgical Research, Volume 31
Effect of autotransplantation of microvessel fragments on experimental random-pattern flaps in the rat
M. Nakano, Y. Nakajima, S. Kudo, Y. Tsuchida, H. Nakamura, O. Fukuda
Jan 1, 1998
European Surgical Research, Volume 30
Direct evidence of a connection between autotransplanted microvessel fragments and the host microvascular system
M. Nakano, Y. Nakajima, S. Kudo, Y. Tsuchida, H. Nakamura, O. Fukuda
Jul 1, 1997
International Journal of Microcirculation, Volume 17
Angiogenic potential of microvessel fragments established in three-dimensional collagen gels
James B. Hoying, Carl A. Boswell, Stuart K. Williams
Jul 1, 1996
In Vitro Cellular & Developmental Biology - Animal, Volume 32
Angiomics Human Adipose Microvessels by Advanced Solutions are for RESEARCH USE ONLY and not for use in humans under any circumstances. Advanced Solutions Life Sciences, LLC. and Advanced Solutions, Inc. are not responsible or liable for how this product is used. The RESEARCH USE ONLY limitation supersedes any written, oral, or implied understanding between the parties.