Automate Single Cell Dispensing with Confidence
What is the PrecisionOne™ Bundle?
PrecisionOne™ is an all-in-one, turnkey solution that streamlines single-cell dispensing and clonal expansion workflows. Whether dispensing one cell at a time for gene editing, assay development, or monoclonality verification, the PrecisionOne™ Bundle performs precise, reliable single-cell operations from “A to Z.”
PrecisionOne helps you:
• Reliably and accurately dispense single cells with high repeatability
• Report clonality with built-in verification tools
• Preserve cell viability with gentle, precision-controlled handling
• Integrate single-cell dispensing into automated workflows
• Includes automated dispensing, passaging, clonal expansion, and more
Optimize throughput, reduce workflow bottlenecks, and increase experimental confidence with the PrecisionOne™ platform built for modern research and therapeutic discovery.
The Challenges + the PrecisionOne™ Solution
• Manual dilution methods reduce efficiency and jeopardize monoclonal integrity
• Stand-alone single-cell dispensers often cannot integrate into automated workflows
• Manual passaging and clonal expansion steps reduce throughput and increases user error
• Failed plates drive up costs and rare-cell recovery is inconsistent
PrecisionOne™ solves these challenges by automating all essential single-cell dispensing and clonal expansion operations in one scalable platform.
Our turnkey single-cell dispensing system performs all steps in a single-cell workflow, improving efficiency and protecting cell health. Automated, high-speed, low-shear workflows keep cells viable while enabling scale-up. Clonal expansion and verification tools increase success rates and support confident rare-cell recovery.
What’s Included in the PrecisionOne Bundle
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• The BioAssemblyBot® - Automated Robotics Engine
• BioApps – Ready-to-use, plug-and-play workflows that save time, reduce setup effort, and let you easily customize and collaborate on your existing processes.
• Customizable Assay Support – Easily adapt to your plates, formats, and downstream analysis
• BAB Hands – Robotic tools for dispensing, plate handling, and more!
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Built on the robust BioAssemblyBot® (BAB) foundation
At the core of our PrecisionOne Bundle is the BioAssemblyBot®, a precision multi-axis robot designed for high-throughput single cell dispensing, and handling. This bundle comes pre-configured with the tools and workflows you need to get started right away-
so you can focus on discoveries, not setup.
PrecisionOne™ BioApps:
Automation, Without Programming
BioApps are preloaded, ready-to-run protocols that automate every step of your organoid workflow - from cell seeding to assay performance. With BioApps, you don’t have to code or script. Just load your plates and reagents, push a button, and walk away.
Each PrecisionOne™ model comes with a curated set of BioApps
Single Cell Dispense
Options: Single Plate, 384 Well Plate, and Four Plates
The Single-Single Cell Dispensing BioApp Automates precise dispensing across multiple plates in a single run, ensuring high-throughput, reproducible single-single cell workflows without compromising cell viability.
Compatibility: All Bundle Models
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Cell Painting
The Cell Painting BioApp Enables precise single-single cell dispensing for accurate cell painting and consistent, reproducible results.
Compatibility: All Bundle Models
Cell Plating
Ensures precise cell distribution for consistent well-to-well density and reliable downstream assays.
Compatibility: Elite400, Elite500, Autonomous400, Autonomous500
Clonal Expansion
The Clonal Expansion BioApp Automates single cell colony selection and expansion, enabling scalable, reproducible growth of clonal populations with minimal manual intervention.
Compatibility: All Bundles
Plate Preparation
Prepares assay-ready multiwell plates for single-cell workflows.
Compatibility: Elite400, Elite500, Autonomous400 and 500
6 Well Passaging BioApp
The 6 Well Plate Passaging BioApp Automates seamless cell transfer from one plate to six, enabling consistent expansion and effortless repeatability.
Compatibility: Elite400, Elite500, Autonomous400, Autonomous500
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Create Your Own
Design custom BioApps based on your existing protocols for seamless integration and flexibility.
Compatibility: All Bundles
The Tools Behind the Automation
You’ve got better things to do than calibrate gear or repeat manual steps all day. The PrecisionOne™ Bundle includes the robotic tools (aka “hands”) that make hands-free workflows possible:
These tools come pre-installed and calibrated - no assembly required.
PrecisionOne™
Advanced Solutions' PrecisionOne™ hand rapidly and precisely dispenses single cells into plates and containers, enhancing efficiency and reliability.
Compatibility: Elite400, Elite500, Autonomous400, Autonomous500
8 Channel Pipette
Advanced Solutions’ 8 Channel Pipette BioAssemblyBot Hand® High-speed liquid handling for media exchange, seeding, compound delivery
Compatibility: Elite400, Elite500, Autonomous400, Autonomous500
Single Channel Pipette
Advanced Solutions’ Pipette BioAssemblyBot Hand® is a ultra-precise pipetting for delicate workflows
Compatibility: All Bundle Models
Pick and Place
Advanced Solutions’ Pick & Place BioAssemblyBot Hand® Automates plate handling for walkaway workflows
Compatibility: All Bundle Models
Automate Precision. Accelerate Discovery.
PrecisionOne™ simplifies single cell dispensing with reliable, automated precision - delivering consistent results while protecting cell health.
Why PrecisionOne™?
• Higher Success Rates – Robotic dispensing reduces human error
• Faster Time-to-Data – Prebuilt workflows accelerate startup
• Reliability – Desired per-well outcomes with clonality reporting
• Reproducibility at Scale – Consistent, verified results across plates and experiments
Tailored for Your Research
Gene Editing
• High-efficiency single-cell dispensing into multiwell plates
• Preserve genomic integrity in iPSCs and edited clones
• Increase confirmed clonal expansions with automated verification
Antibody Discovery
• Isolate rare B cells with minimal doublets
• Improve plate success rates and reduce costly repeats
• Maintain viability for sequencing and downstream screening
Vaccine Development
• High-throughput immune-cell isolation for large-scale studies
• Gentle handling for fragile T- and B-cell phenotypes
• Seamless integration into multi-omics workflows
PrecisionOne™: your all-in-one solution for automated single cell dispensing bundle.
BAB dispensed microspheres/cells with relatively high efficiency and reliability with the real-time reporting by BAB of each dispense event was ~97% (for microspheres) and ~92% (for cells). A report generated by BAB for a dispensing run includes a reliability map (generated in real time) of the dispensing outcomes, a histogram of impedance values for the run, elapsed time for the individual steps, and impedance data for each well.
Take the next step toward high-throughput, reproducible single cell research.
Schedule a Demo with our automation experts today and see how PrecisionOne can transform your lab.
