Bench-Ready Organoid Discovery System
Plug-and-play automation that reduces human error, boosts capacity, and accelerates drug discovery
What is Organoid360™?
Organoid360™ is a turnkey automation platform for organoid research and drug discovery, combining the precision robotics of the BioAssemblyBot® with specialized tools (BAB Hands) and ready-to-use protocols (BioApps.) This out-of-the-box solution streamlines human-relevant or NAMs-friendly work by automating organoid assay set-up through consistently executing cell plating, media exchanges, spheroid formation and T-cell activation protocols. Designed to accelerate drug screening and provide reliable alternatives to animal testing, Organoid360™ empowers researchers with reproducible, high-throughput performance that aligns with NIH funding priorities and advances next-generation organoid models.
Supporting FDA new approach methodologies (NAMs)
What’s Included in the Organoid360™ Bundled System?
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BioAssemblyBot® – automated robotics engine
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BioApps – pre-installed plug-and-play workflows
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BioApps enable users to create workflows and collaborate on pre-existing protocols
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Robotic tools – for pipetting, plate handling & more
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NAMs-ready – supports multiwell assay formats
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5 model bundles – to fit labs of all sizes and budgets
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Organoid360™ isn’t just a robot—it’s your turnkey organoid research assistant.
Organoid360™ is a ready-to-run system, no need for programming. It's more than a robot—it’s your full organoid research assistant.
Elite400 Bundle
BAB Hands
BioApps
BAB400
Essentials Bundle
BAB Hands
BioApps
BAB200
Elite500 Bundle
BAB500
BAB Hands
BioApps
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Built on the robust
BioAssemblyBot® foundation
At the heart of Organoid360™ is the BioAssemblyBot®, a versatile, multi-axis robotic system capable of executing complex 3D tissue modeling, specialized operations, liquid handling, and material transfer tasks. What makes Organoid360™ unique is how this core engine is pre-configured and bundled with the exact tools and workflows you need for organoid research - so you can get started immediately.
Five models. One system. All optimized for human tissue-relevant results.
Organoid360™ Bundles starting at $110,000!
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Organoid360™ BioApps:
Automation, Without Programming
BioApps are preloaded, ready-to-run protocols that automate every step of your organoid workflow - from cell seeding to assay performance. With BioApps, you don’t have to code or script. Just load your plates and reagents, push a button, and walk away.
Each Organoid360™ model comes with a curated set of BioApps
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Organoid Assay BioApp
The Organoid Assay BioApp Automates the fabrication and maintenance of spheroid/organoid dome assays for high-throughput screening.
Compatibility: All Bundle Models
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T-Cell Activation Assay BioApp
The T-Cell Activation BioApp Drives immunology assays by automating T-lymphocyte activation screens.
Compatibility: All Bundle Models
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Cell Plating BioApp
The Cell Plating BioApp Ensures precise cell distribution for organoid formation and consistent well-to-well results.
Compatibility: All Bundle Models
Drug Discovery BioApp
The Drug Discovery BioApp Automates time-course drug dilution, delivery and high-throughput treatment screens.
Compatibility: All Bundle Models
Plate Preparation BioApp
Prepares assay-ready multiwell plates for organoid workflows.
Compatibility: Elite400, Elite500, Autonomous400, Autonomous500
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Create Your Own
Design custom BioApps based on your existing protocols for seamless integration and flexibility.
Compatibility: All Bundles
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At Advanced Solutions, we are organoid type agnostic.
Whether your research focuses on brain, liver, kidney, intestinal, lung, pancreatic, retinal, heart, or tumor organoids, our Organoid360™ Bundle is designed to support your unique models.
Your discoveries shouldn’t be limited by your tools.
The Tools Behind the Automation
You’ve got better things to do than calibrate gear or repeat manual steps all day. Organoid360™ includes the robotic tools (aka “hands”) that make hands-free workflows possible:
8 Channel Pipette
Advanced Solutions’ 8 Channel Pipette BioAssemblyBot Hand® High-speed liquid handling for media exchange, seeding, compound delivery
Compatibility: Elite400, Elite500, Autonomous400, Autonomous500
Single Channel Pipette
Advanced Solutions’ Pipette BioAssemblyBot Hand® is a ultra-precise pipetting for delicate workflows
Compatibility: All Bundle Models
Pick and Place
Advanced Solutions’ Pick & Place BioAssemblyBot Hand® Automates plate handling for walkaway workflows
Compatibility: All Bundle Models
These tools come pre-installed and calibrated - no assembly required.
Automation That Performs
Explore how robotic precision transforms organoid workflows - from faster pipetting to flawless plate handling. This section highlights the measurable impact of automation, with visuals, stats, and side-by-side comparisons that show just how much time, effort, and variability you save when you hand it off to the bot.
Robot vs. Human: Tumor Spheroid Workflow Comparison
Automated workflows built with Organoid360™ and BioApps produce spheroids with greater consistency and speed compared to manual methods.
Visuals, stats, and timelines show the measurable impact:
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Lower variability
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Reduced hands-on time
Case Study: CRC PDO Drug Screen
Organoid360™ accelerates PDO-based assay workflows, improves data quality, and enables high-throughput drug discovery.
Spheroid Size Over Time in Culture. The average spheroid diameter was measured daily using transmitted light images acquired with the ImageXpress® scanner, comparing manual and automated workflows. Spheroids in the automated workflow (using the BioAssemblyBot®) were significantly larger than those in the manual workflow (p ≤ 0.01, Mann-Whitney test). This increase in size reflects that the BAB left the organoids intact, while the manual method led to fragmentation by the scientist.
Patient Derived Organoid
BioAssemblyBot enabled consistency across every well
#BABImpact
The profound and positive impact with the help of BAB, the BioAssemblyBot™
“ASLS has been a great partner and BAB has helped us deliver consistent, robust data from our stem cell biology and 3D biofabrication programs for developing bioengineered kidneys. The speed and reproducibility has been integral to our evaluation of therapeutic tissue strategies.”
- Ben Shepherd,
Trestle Bio Co-Founder and CEO.
“The BioAssemblyBot has made it easy to complete the experiments we proposed in our grant applications and get to breakthroughs faster.”
Professor Liisa Kuhn, University of Connecticut Health Center
"BioAssemblyBot and Angiomics biofabrication platforms are valuable inventions and contributions toward our ARMI mission to mass produce human organs. Advanced Solutions is the poster child company for the ARMI ecosystem. The team is entrepreneurial, talented, and leading members for ARMI."
Dean Kamen, Executive Director of ARMI
