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Organoid360: Automated Organoid Culture & Drug Screening

Organoid360 is a pre-configured, turnkey system for automated organoid culture, organoid screening and 3D cell culture. This out-of-the-box solution combines the precision robotics of the BioAssemblyBot® with application-specific hardware (BAB Hands) and pre-built protocols (BioApps) - all optimized for organoid-based research and drug discovery.​ 

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Power it on. Pick one of the pre-loaded BioApps. And go.

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Built for the 3D work you're already doing.

Organoids, spheroids, and patient-derived models are hard to handle by hand. Organoid360 makes that work faster and more consistent.

Organoid Screening, Automated

Screening patient-derived organoids (PDOs) means hundreds of domes, drug treatments, and readouts, and every one has to be consistent. In our colorectal cancer PDO drug screen, the automated workflow formed Matrigel domes faster and more accurately than manual pipetting, prepared the drug treatments, and picked up differences in drug response between patients’ tumor organoids. That’s the consistency high-content screening depends on.

Spheroids and 3D Cell Culture

Pipetting by hand can break spheroids apart before your experiment even starts. In a tumor spheroid workflow built with Organoid360 and BioApps, automation formed clear Matrigel domes in 81% of wells (vs. 72% by hand) in 10 min 40 s (vs. 15 min). It also kept the spheroids intact: 2.0 per dome, as seeded, vs. 6.2 by hand, where pipetting had fragmented them.

Ready for Your Organoid Models

Every model has its own needs. Organoid360 is designed to support your organoid models, including brain, liver, kidney, and more. Pre-built BioApps and BAB Hands cover the core 3D cell culture steps, and you can adjust protocols to fit your research instead of building automation from scratch.

Process
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Essentials

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For labs begining organoid automation

  • Generate Matrigel domes for organoid culture

  • Activate T-Cells for immunology workflows

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Elite400

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For growing research programs

  • Generate Matrigel domes for organoid culture

  • Plate cells with precision for well-to-well seeding

  • Prepare assay plates with media & reagents

  • Prepare Drug treatments with consistency

  • Activate T-Cells for immunology workflows

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Elite500

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For high-containment research enviornments

  • Generate Matrigel domes for organoid culture

  • Plate cells with precision for well-to-well seeding

  • Prepare assay plates with media & reagents

  • Prepare Drug treatments with consistency

  • Activate T-Cells for immunology workflows

  • Protect your workspace with biosafety cabinet

We Are Organoid-Type Agnostic

Whether your research focuses on brain, liver, kidney, intestinal, lung, pancreatic, retinal, heart, or tumor organoids, our Organoid360™ Bundle is designed to support your unique models.

 

Your discoveries shouldn’t be limited by your tools.

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  • Liver

  • Retinal

  • Tumor

  • Intestinal

  • Cardiac

  • Brain

  • Kidney

  • Lung

  • Pancreatic

Features & Benefits

Plug & Play Automation

Accelerate Drug Discovery

Reduce Human Error

NAMs- Ready

Boost Capacity

No Coding Needed

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Tell Us About Your Organoid Workflow

Tell us what’s slowing your organoid work down. An organoid specialist will follow up within one business day to walk through how Organoid360 and BioAssemblyBot fit your lab.

Featured Resources

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Case Study: Patient-Derived Organoid (PDO) Drug Screen

Organoid360™ accelerates patient-derived organoid assays and organoid drug screening, improves data quality, and enables high-throughput drug discovery.

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Robot vs. Human: Tumor Spheroid Workflow Comparison

Automated workflows built with Organoid360™ and BioApps produce spheroids with greater consistency and speed compared to manual methods. 

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