Bench-Ready Organoid Discovery System
Plug-and-play automation that reduces human error, boosts capacity, and accelerates drug discovery
What is Organoid360™?
Organoid360™ is a pre-configured, turnkey automation system purpose-built for organoid workflows. This out-of-the-box solution combines the precision robotics of the BioAssemblyBot® with application-specific hardware (BAB Hands) and pre-built protocols (BioApps) - all optimized for organoid-based research and drug discovery.
Organoid360™ isn’t just a platform - it’s a complete system for automating organoid assays at scale, engineered to perform critical tasks like cell plating, media exchanges, spheroid formation, T-cell activation assays, and more. Whether you're building organoid assays, running drug screens - Organoid360™ empowers your team with reproducible, high-throughput performance at the push of a button.
Supporting FDA new approach methodologies (NAMs)
Breakthrough Roadblocks
With Organoid360™
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What’s Included in the Organoid360™ System?
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BioAssemblyBot® – automated robotics engine
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BioApps – pre-installed plug-and-play workflows
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Robotic tools – for pipetting, plate handling & more
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NAMs-ready – supports multiwell assay formats
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5 model bundles – to fit labs of all sizes and budgets
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Organoid360™ isn’t just a robot—it’s your turnkey organoid research assistant.
Organoid360™ is a ready-to-run system, no need for programming. It's more than a robot—it’s your full organoid research assistant.
Built on the robust
BioAssemblyBot® foundation
At the heart of Organoid360™ is the BioAssemblyBot®, a versatile, multi-axis robotic system capable of executing complex 3D tissue modeling, specialized operations, liquid handling, and material transfer tasks. What makes Organoid360™ unique is how this core engine is pre-configured and bundled with the exact tools and workflows you need for organoid research - so you can get started immediately.
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Hands-free workflows for organoid assay setup & maintenance
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Turnkey BioApps for cell plating, drug dosing, organoid derivation, organoid dome assays, and T-cell activation assays
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Pre-installed robotic tools for workflow tasks including pipetting and plate management with organoids
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Options for laboratory needs across five models
Five models. One system. All optimized for human tissue-relevant results.
Whether you need entry-level automation or fully autonomous integration, there's an Organoid360™ model for your lab
Organoid360™ Bundles starting at $110,000!
Elite400 Bundle
BAB Hands
BioApps
BAB400
Essentials Bundle
BAB Hands
BioApps
BAB200
Elite500 Bundle
BAB500
BAB Hands
BioApps
Customizable Solutions
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Schedule a demo with our specialists today!
Organoid360™ BioApps:
Automation, Without Programming
BioApps are preloaded, ready-to-run protocols that automate every step of your organoid workflow - from cell seeding to assay performance. With BioApps, you don’t have to code or script. Just load your plates and reagents, push a button, and walk away.
Each Organoid360™ model comes with a curated set of BioApps
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Organoid Assay BioApp
The Organoid Assay BioApp Automates the fabrication and maintenance of spheroid/organoid dome assays for high-throughput screening.
Compatibility: All Bundle Models
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T-Cell Activation Assay BioApp
The T-Cell Activation BioApp Drives immunology assays by automating T-lymphocyte activation screens.
Compatibility: All Bundle Models
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Cell Plating BioApp
The Cell Plating BioApp Ensures precise cell distribution for organoid formation and consistent well-to-well results.
Compatibility: All Bundle Models
Drug Discovery BioApp
The Drug Discovery BioApp Automates time-course drug dilution, delivery and high-throughput treatment screens.
Compatibility: All Bundle Models
Plate Preparation BioApp
Prepares assay-ready multiwell plates for organoid workflows.
Compatibility: Elite400, Elite500, Autonomous400, Autonomous500
The Tools Behind the Automation
You’ve got better things to do than calibrate gear or repeat manual steps all day. Organoid360™ includes the robotic tools (aka “hands”) that make hands-free workflows possible:
8 Channel Pipette
Advanced Solutions’ 8 Channel Pipette BioAssemblyBot Hand® High-speed liquid handling for media exchange, seeding, compound delivery
Compatibility: Elite400, Elite500, Autonomous400, Autonomous500
Single Channel Pipette
Advanced Solutions’ Pipette BioAssemblBot Hand® is a ultra-precise pipetting for delicate workflows
Compatibility: All Bundle Models
Pick and Place
Advanced Solutions’ Pick & Place BioAssemblBot Hand® Automates plate handling for walkaway workflows
Compatibility: All Bundle Models
These tools come pre-installed and calibrated - no assembly required.
Automation That Performs
Explore how robotic precision transforms organoid workflows - from faster pipetting to flawless plate handling. This section highlights the measurable impact of automation, with visuals, stats, and side-by-side comparisons that show just how much time, effort, and variability you save when you hand it off to the bot.
Robot vs. Human: Tumor Spheroid Workflow Comparison
Automated workflows built with Organoid360™ and BioApps produce spheroids with greater consistency and speed compared to manual methods.
Visuals, stats, and timelines show the measurable impact:
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Lower variability
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Reduced hands-on time
Case Study: CRC PDO Drug Screen
Organoid360™ accelerates PDO-based assay workflows, improves data quality, and enables high-throughput drug discovery.
Spheroid Size Over Time in Culture. The average spheroid diameter was measured daily using transmitted light images acquired with the ImageXpress® scanner, comparing manual and automated workflows. Spheroids in the automated workflow (using the BioAssemblyBot®) were significantly larger than those in the manual workflow (p ≤ 0.01, Mann-Whitney test). This increase in size reflects that the BAB left the organoids intact, while the manual method led to fragmentation by the scientist.
Patient Derived Organoid
BioAssemblyBot enabled consistency across every well
#BABImpact
The profound and positive impact with the help of BAB, the BioAssemblyBot™
“ASLS has been a great partner and BAB has helped us deliver consistent, robust data from our stem cell biology and 3D biofabrication programs for developing bioengineered kidneys. The speed and reproducibility has been integral to our evaluation of therapeutic tissue strategies.”
- Ben Shepherd,
Trestle Bio Co-Founder and CEO.
“The BioAssemblyBot has made it easy to complete the experiments we proposed in our grant applications and get to breakthroughs faster.”
Professor Liisa Kuhn, University of Conneticut Health Center
