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Organoid360 platform enabling high-throughput, automated generation and analysis of 3D organoids for drug discovery and disea

Bench-Ready Organoid Discovery System 

Plug-and-play automation that reduces human error, boosts capacity, and accelerates drug discovery

Organoid_Spheroid Research

What is Organoid360™?

Organoid360™ is a pre-configured, turnkey automation system purpose-built for organoid workflows. This out-of-the-box solution combines the precision robotics of the BioAssemblyBot® with application-specific hardware (BAB Hands) and pre-built protocols (BioApps) - all optimized for organoid-based research and drug discovery.​

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Organoid360™ isn’t just a platform - it’s a complete system for automating organoid assays at scale, engineered to perform critical tasks like cell plating, media exchanges, spheroid formation, T-cell activation assays, and more. Whether you're building organoid assays, running drug screens - Organoid360™ empowers your team with reproducible, high-throughput performance at the push of a button. 

Supporting FDA new approach methodologies (NAMs)

Breakthrough Roadblocks 

With Organoid360™

Alleviate road blocks in lab work with Organoid360
Alleviate road blocks in lab work with Organoid360
Alleviate road blocks in lab work with Organoid360

What’s Included in the Organoid360™ System?

 

  • BioAssemblyBot® – automated robotics engine

  • BioApps – pre-installed plug-and-play workflows

  • BioApps enable users to create workflows and collaborate on pre-existing protocols 

  • Robotic tools – for pipetting, plate handling & more

  • NAMs-ready – supports multiwell assay formats

  • 5 model bundles – to fit labs of all sizes and budgets

  • Organoid360™ isn’t just a robot—it’s your turnkey organoid research assistant.

 

Organoid360™ is a ready-to-run system, no need for programming. It's more than a robot—it’s your full organoid research assistant.

Built on the robust
BioAssemblyBot® foundation

At the heart of Organoid360™ is the BioAssemblyBot®, a versatile, multi-axis robotic system capable of executing complex 3D tissue modeling, specialized operations, liquid handling, and material transfer tasks. What makes Organoid360™ unique is how this core engine is pre-configured and bundled with the exact tools and workflows you need for organoid research - so you can get started immediately.

  • Hands-free workflows for organoid assay setup & maintenance

  • Turnkey BioApps for cell plating, drug dosing, organoid derivation, organoid dome assays, and T-cell activation assays, and allows you to create custom workflows to collaborate with pre-existing protocols 

  • Pre-installed robotic tools for workflow tasks including pipetting and plate management with organoids

  • Options for laboratory needs across five models

Organoid assay setup for evaluating drug responses and toxicity in 3D tissue models mimicking human organ function

 Five models. One system. All optimized for human tissue-relevant results. 

Whether you need entry-level automation or fully autonomous integration, there's an Organoid360™ model for your lab

Organoid assay setup for evaluating drug responses and toxicity in 3D tissue models mimicking human organ function

Organoid360™ Bundles starting at $110,000!

Array of interchangeable BioAssemblyBot hands including pipetting, printing, pick-and-place, and imaging tools designed for v
BioApps.pngBioApps software platform providing modular, automated workflows for 3D bioprinting, liquid handling, and tissue c

Elite400 Bundle

BAB Hands
BioApps
* BioAssemblyBot 400 with integrated smart sensors and interchangeable tools for scalable and reproducible biofabrication.
BAB400

Essentials Bundle

BAB Hands
BioApps
BAB200
* BioAssemblyBot 200 compact robotic bioprinter designed for benchtop use in cell biology and tissue engineering workflows.
Comprehensive BioApps suite streamlining multi-step bioprocess automation for enhanced throughput and consistency in tissue e
BioAssemblyBot hands facilitating high-throughput, automated workflows with accuracy and flexibility in organoid and regenera
BioAssemblyBot 500 with expanded workspace and multi-tool integration for complex 3D bioprinting, dispensing, and imaging wor
BioApps software platform providing modular, automated workflows for 3D bioprinting, liquid handling, and tissue culture in r
Array of interchangeable BioAssemblyBot hands including pipetting, printing, pick-and-place, and imaging tools designed for v

Elite500 Bundle

BAB500
BAB Hands
BioApps
Create your own BioApp to design custom workflows that complement and integrate with pre-existing protocols
Create your own BioApp to design custom workflows that complement and integrate with pre-existing protocols
Create your own BioApp to design custom workflows that complement and integrate with pre-existing protocols

Customizable Solutions

Checklist showing items included in the Organoid360 Bundle: bioprinter, imaging system, culture media, software, and protocol

Schedule a demo with our specialists today!

Organoid360™ BioApps:

Automation, Without Programming

BioApps are preloaded, ready-to-run protocols that automate every step of your organoid workflow - from cell seeding to assay performance. With BioApps, you don’t have to code or script. Just load your plates and reagents, push a button, and walk away.

Each Organoid360™ model comes with a curated set of BioApps 

Organoid360 platform enabling highly reproducible generation and analysis of 3D organoids, ensuring consistent tissue models
Comprehensive BioAssemblyBot platform enabling automated fabrication of complex 3D tissue models with controlled spatial patt
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Organoid Assay BioApp​

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The Organoid Assay BioApp Automates the fabrication and maintenance of spheroid/organoid dome assays for high-throughput screening.​

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Compatibility: All Bundle Models

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T-Cell Activation Assay BioApp ​

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The T-Cell Activation BioApp Drives immunology assays by automating T-lymphocyte activation screens.

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Compatibility: All Bundle Models 

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Cell Plating BioApp

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The Cell Plating BioApp Ensures precise cell distribution for organoid formation and consistent well-to-well results. 

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Compatibility: All Bundle Models 
 

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Drug Discover

Drug Discovery BioApp​

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The Drug Discovery BioApp Automates time-course drug dilution, delivery and high-throughput treatment screens.

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Compatibility: All Bundle Models 

Plate Prep

Plate Preparation BioApp

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Prepares assay-ready multiwell plates for organoid workflows. 

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Compatibility: Elite400, Elite500, Autonomous400, Autonomous500

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Create Your Own ​

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Design custom BioApps based on your existing protocols for seamless integration and flexibility.​

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Compatibility: All Bundles

Apps Anchor
Comprehensive BioAssemblyBot platform enabling automated fabrication of complex 3D tissue models with controlled spatial patt

The Tools Behind the Automation ​​

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You’ve got better things to do than calibrate gear or repeat manual steps all day. Organoid360™ includes the robotic tools (aka “hands”) that make hands-free workflows possible: 

BioAssemblyBot equipped with an 8-channel pipette hand for high-throughput liquid handling and precise multi-well dispensing

8 Channel Pipette ​

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Advanced Solutions’ 8 Channel Pipette BioAssemblyBot Hand® High-speed liquid handling for media exchange, seeding, compound delivery 

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Compatibility: Elite400, Elite500, Autonomous400, Autonomous500

Single Channel Pipette ​

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Advanced Solutions’ Pipette BioAssemblyBot Hand® is a ultra-precise pipetting for delicate workflows 

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Compatibility: All Bundle Models 

Pick and Place ​

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Advanced Solutions’ Pick & Place BioAssemblyBot Hand® Automates plate handling for walkaway workflows 
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Compatibility: All Bundle Models 

BioAssemblyBot equipped with a single-channel pipette hand for precise, targeted liquid handling and dispensing in automated
BioAssemblyBot equipped with a pick-and-place hand for precise manipulation and transfer of tissue constructs, scaffolds, and

These tools come pre-installed and calibrated - no assembly required.

Hands Anchor

Automation That Performs 

Explore how robotic precision transforms organoid workflows - from faster pipetting to flawless plate handling. This section highlights the measurable impact of automation, with visuals, stats, and side-by-side comparisons that show just how much time, effort, and variability you save when you hand it off to the bot. 

Robot vs. Human: Tumor Spheroid Workflow Comparison 

Automated workflows built with Organoid360™ and BioApps produce spheroids with greater consistency and speed compared to manual methods. 

 

Visuals, stats, and timelines show the measurable impact: 

  • Lower variability 

  • Reduced hands-on time 

Case Study: CRC PDO Drug Screen 

Organoid360™ accelerates PDO-based assay workflows, improves data quality, and enables high-throughput drug discovery.

BioAssemblyBot delivering consistent, high-quality results in automated 3D bioprinting and tissue fabrication workflows, enab

Spheroid Size Over Time in Culture. The average spheroid diameter was measured daily using transmitted light images acquired with the ImageXpress® scanner, comparing manual and automated workflows. Spheroids in the automated workflow (using the BioAssemblyBot®) were significantly larger than those in the manual workflow (p ≤ 0.01, Mann-Whitney test). This increase in size reflects that the BAB left the organoids intact, while the manual method led to fragmentation by the scientist.

colorectal cancer patient-derived organoids (CRCPDO) cultured in 3D matrix, used for personalized cancer drug testing.

Patient Derived Organoid

BioAssemblyBot enabled consistency across every well 

Doctor with Tablet

Interested in how the Organoid360™ Bundle could breakthrough roadblocks in your lab? Connect with a specialist today!

Platforms starting at $110,000

Pipette Inserted Into Test Tube

#BABImpact
The profound and positive impact with the help of BAB, the BioAssemblyBot™

Ben Shepherd utilizing the BioAssemblyBot platform to automate 3D bioprinting workflows for developing bioengineered kidney t

“ASLS has been a great partner and BAB has helped us deliver consistent, robust data from our stem cell biology and 3D biofabrication programs for developing bioengineered kidneys.  The speed and reproducibility has been integral to our evaluation of therapeutic tissue strategies.” 

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- Ben Shepherd,

Trestle Bio Co-Founder and CEO. 

Lisa Kamen leveraging BioAssemblyBot’s precision multi-tool capabilities to fabricate vascularized organoids for regenerative

“The BioAssemblyBot has made it easy to complete the experiments we proposed in our grant applications and get to breakthroughs faster.” 

 

 

 Professor Liisa Kuhn, University of Connecticut Health Center 

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Dean Kamen, inventor and founder of DEKA Research, known for pioneering innovations in medical technology and engineering.

"BioAssemblyBot and Angiomics biofabrication platforms are valuable inventions and contributions toward our ARMI mission to mass produce human organs. Advanced Solutions is the poster child company for the ARMI ecosystem. The team is entrepreneurial, talented, and leading members for ARMI."

Dean Kamen, Executive Director of ARMI

Connect with a Specialist Today!

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