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Human Heart Recellularization with Dr. Doris Taylor

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Create a personalized human heart replacement.

BioAssemblyBot® (#WeCallHerBAB) now offers a way to robotically add patient stem cells back to a decellularized heart and bring it back to life.        

Transfer processes to close and automate them.

When we eliminate human interaction and contamination, new speeds and possibilities are within reach.

First Bioengineered Human Heart

Dr. Doris Taylor, CEO and founder of Organamet Bio, shows off her ground-breaking process for creating the World’s first bioengineered human heart.  Dr. Taylor is teaching BAB her recellularization techniques in order to provide a quicker transition of her research into a clinical setting.  Her talk took place on stage at the 2022 Life Itself conference, a health event presented in partnership with CNN.

BAB learns complex processes.

Dr. Doris Taylor taught BAB to her method of injecting 350 billion cells into a heart scaffold, enabling the automation and creation of a personalized human heart fast enough to realistically enable on-demand bio-engineered human heart transplants. 

Increase Availability and Access.

With ready-made heart replacements, gone are the days of waiting on a transplant list.

Ready-made heart replacements increasing availability and eliminating wait times for transplants
Embryonic stem cells with the ability to differentiate into various specialized cell types

Eliminate Immunosuppression.

Built from an individual’s own cells, the bio-engineered heart replacement won't be rejected and without the use of antirejection medication.

Reduce Total Transplant Costs.

By creating a heart from scratch, a transplant does not mean trading one life for another.

Creating hearts from scratch reduces total transplant costs and avoids trading one life for another
Planned heart transplants allowing patients to schedule proactive procedures instead of waiting for emergencies

Plan Heart Transplants.

Unlike traditional heart transplants, if you know you have a problem, you don't need to wait for an emergency to receive a transplant. Plan and schedule a transplant proactively.

BioAssemblyBot 200 compact bioprinter operating inside a biosafety cabinet for sterile 3D biofabrication
BioAssemblyBot 400 mid-sized bioprinter performing automated 3D biofabrication workflows
BioAssemblyBot 500 large-format bioprinter with multi-tool capabilities for complex 3D biofabrication
BioAssemblyBot 200 compact bioprinter operating inside a biosafety cabinet for sterile 3D biofabrication
BioAssemblyBot 400 mid-sized bioprinter performing automated 3D biofabrication workflows
BioAssemblyBot 500 large-format bioprinter with multi-tool capabilities for complex 3D biofabrication

Applications

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Academic (College)


Research & Development


Pharma


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Academic (College)


Research & Development


Pharma


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Academic (College)


Research & Development


Pharma


Clinical

Features

Build simple to moderately complex disease models


3D Additive Models



Great

Identify new molecular targets


Good

Develop new drugs


3D Print in Well Plates


4-axis Robot


Biosafety Cabinet Compatible (without enclosure)


HEPA Filtration Optional

Build simple to highly complex disease models


3D Additive & Contour Models


Great

Identify new molecular targets


Great

Develop new drugs


3D Print in Well Plates


6-axis Robot


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HEPA Filtration Optional

Build simple to highly complex disease models


3D Additive & Contour Models


Great

Identify new molecular targets


Great

Develop new drugs


3D Print in Well Plates


6-axis Robot


Integrated Class II, Type A Biosafety Cabinet


Integrated HEPA Filtration

Certifications

TSIM Certified


BioApps Certified


UL cGMP Certified


UL/CE Certification in progress

TSIM Certified


BioApps Certified


UL cGMP Certified


UL/CE Certified

TSIM Certified


BioApps Certified


UL cGMP Certified


UL/CE Certification in progress

Integrations

Up to 5 BioAssemblyBot Hands in a single run


Good

Agile integration with other lab equipment

Up to 8 BioAssemblyBot Hands in a single run


Great*

Agile integration with other lab equipment

Up to 10 BioAssemblyBot Hands in a single run


Great*

Agile integration with other lab equipment

*Requires BioBot Link

BioAssemblyBot 200 compact bioprinter operating inside a biosafety cabinet for sterile 3D biofabrication
BioAssemblyBot 400 mid-sized bioprinter performing automated 3D biofabrication workflows
BioAssemblyBot 500 large-format bioprinter with multi-tool capabilities for complex 3D biofabrication

Explore more solutions:

3D bioprinter depositing bioinks layer-by-layer to create living tissue constructs

3D Bioprinting

Bioprint in ways you never thought possible.
Composite tissue construct combining multiple biomaterials and cell types for enhanced functionality

Organoids/
Spheroids

One platform, better outcomes.
3D bioprinted tissue with developing vascular networks supporting nutrient and oxygen flow

Vascularization

Bring your tissue to life.
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3ATM Quote
UL certification label indicating safety compliance of biomanufacturing equipment

The BioAssemblyBot 400 is certified by UL in accordance with applicable safety requirements. The BioAssemblyBot 400 is certified by UL in accordance with applicable energy efficiency requirements.

The Advanced Solutions Louisville, KY facility has been audited by UL Registrar LLC and meets GMP requirements listed in RCP, NBCP, or Pharmaceutical Certification Schemes which is uniquely accredited by the American National Standard Institute (ANSI) developed in accordance with applicable sections of the FDA’s code of federal regulations.

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